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A fixed SEEG classifier exceeded shaft label controls when each of 34 test patients was excluded from training

We tested a fixed SEEG power classifier in 34 patients from OpenNeuro ds004100 version 1.1.3. Each test patient was excluded from training. The primary rule subtracted each patient's median log power in seven bands. Mean patient AUC was 0.62786 in run 01. The mean shaft label control AUC was 0.54784. None of 9,999 control draws reached the observed mean. The upper-tail Monte Carlo p value was 0.0001. The control assumes uniform label allocation within each patient and shaft, with positive counts fixed. Both training and test labels changed in every draw. Median subtraction did not increase the observed mean AUC in either recording. The paired changes were -0.02911 and -0.00954. Descriptive fixed-score intervals included zero. All four models had higher mean Brier loss than a training prevalence baseline. A proof shows that median subtraction removes constant patient band offsets under fixed contact and feature rules. Fresh signal ranges reproduced all 70 source spectra exactly. A complete local replay reproduced all scores and control distributions exactly. The package contains code, features, labels, model maps, controls, source pins, checks, figures, and rerun instructions. The scope is one reused epilepsy cohort and clinical contact labels. The test does not establish surgical benefit or external validation.

stereoelectroencephalography · seizure onset zone · patient exclusion · nearest neighbors · AUC · label controls · median subtraction · Brier loss

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References

4
  1. usesContact splits gave higher mean pooled AUC for seizure onset labels than shaft splits with a fixed spectral random forest in 34 SEEG patients sci:sha256:56a9020d2fcfaf8dce31031e250ead4147aed4b96d5049afb0ef063a225a356e

    We reused its seven-band contact table and cohort exclusions through the parent package. We retained the 34 patients, 4,031 numbered good contacts, and 350 clinical SOZ labels per recording. The table was rebuilt from pinned spectra and channel metadata.

  2. usesMedian 80–150 Hz power rank agreement was lower between references than between recordings on matched pairs in 35 SEEG participants sci:sha256:eaad9a72db87113b65f5fda15f4c3043dc3463ac2f155c6b9d8b01404ec3ab9f

    We reused its pinned common average spectra, metadata, EDF reader, extraction code, and range receipts through the parent package. Fresh public range requests reproduced all 2,659,806 spectral values exactly as float32.

  3. usesA fixed SEEG power classifier gave higher AUC than shaft label controls in 34 patients with two recordings each sci:sha256:8a89343890ef98e61996c482db855f64a4721c2ad4d42b56e10e6d9542567547

    We used its verified source package, fixed five-neighbor rule, seven band features, cohort, and joint training and test label controls. We replaced contact and whole-shaft splits with exclusion of every contact from each test patient. We added label-free patient median subtraction and a prevalence loss baseline.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source SEEG recordings and clinical contact labels came from OpenNeuro ds004100 version 1.1.3; the exact version and CC0 license are recorded in the publication and source metadata.

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