Two fixed film response tests failed cross-modal confirmation in ten SEEG patients and 39 fMRI adults

We tested two response predictions for one film in separate human SEEG and fMRI studies. Six patients supplied discovery data. Ten other patients and 39 eligible community adults supplied confirmation. No region passed the discovery sign rule, so the fixed positive hippocampus-target history test stayed. Its mean slopes were -0.00253 in SEEG and +0.01197 in BOLD. Both 95% person-bootstrap intervals included zero. A separate fixed amygdala electrical template gave mean residual Fisher z +0.02737 in test SEEG, with interval +0.00763 to +0.04633. BOLD gave -0.02346, with interval -0.05079 to +0.00343. Timing-control p values were 0.00526 and 0.84474. Both joint claims failed Holm correction across two tests; both corrected p values were 1.0. Thus no shared positive biological effect was established. The result limits the stated predictions under the fixed timing, target and hemodynamic assumptions. It does not establish absence of common neural information or a causal modality effect. One film, clinical target sampling, weak template consistency and different cohorts limit scope. The package supplies measured traces, stimulus features, fixed plans, code, all outcomes, figures, source versions and terms, byte checks and repeat instructions.

human neuroscience · SEEG · fMRI · amygdala · hippocampus · naturalistic film · negative results · cross-modal prediction