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Fixed cubic heat tests passed in 70 EEG and 23 fMRI adults; another EEG test and some MRI template tests failed

We tested a contrast that is zero for every quadratic heat response curve. Separate public studies supplied laser EEG and BOLD fMRI. Development used 25 EEG adults and ten MRI adults. A local plan, code lock and fixed directions preceded scores in 70 other EEG adults and 23 other MRI adults. Mean cubic scores were 0.09897 and 0.05245. Their 95% person intervals were [0.02809,0.16984] and [0.00656,0.09834]. The shared mean test passed three-claim Holm correction, p=0.026952. The quadratic contrast also passed. Removing some development adults made the MRI cubic test fail; its raw p reached 0.22124. Thus the positive result depends on the fixed template. A stricter one-pattern mean test failed across modalities, p=0.257014, under a normal model of person variation. A separate EEG experiment supplied 23 eligible records. Its quadratic check passed, but its cubic and rank checks failed; cubic Holm p=0.108140. Identity independence across the anonymous EEG releases was not verified. All fixed feature checks had positive pointwise mean intervals. A later source audit restored 1053 EEG epochs with valid intensity without requiring valid reports. Both EEG means stayed positive with the original directions. We retain all outcomes. Exact weights, separate arithmetic and source checks passed. One nonlinear scalar can give both contrasts. The result concerns processed means and the stated dose coordinates. It does not establish stable cubic transfer, several neural sources, pain specificity or a cause. Cohort, input, source selection and measurement differences limit scope. The package gives code, permitted compact EEG data, source pins and terms, all results, figures, plans and repeat steps. Original MRI maps stay external.

EEG · fMRI · heat intensity · polynomial contrast · held-out people · population response rank · uncertainty

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References

12
  1. usesFixed models did not confirm shared gains for heat ratings in 70 EEG adults and 23 fMRI adults sci:sha256:d31b48e213887bcecdf56aca37d6a2a99dde99b8eff9b24b4056a23d43108d81

    We reuse its CC0-derived compact EEG features and MIT source preparation code. Our new endpoints test polynomial response contrasts and population mean rank, not its report-prediction claims.

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