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A test that assumed independent patients and symmetric null contrasts did not detect lower beta power map agreement across stimulation intervals in 21 SEEG patients

We tested beta power map rank agreement in 35 released recordings from 21 patients with epilepsy in OpenNeuro ds006519 version 1.0.0. Two-second windows used power from 13 through 29 Hz. A test that assumed independent patients and symmetric null contrasts did not detect lower agreement across stimulation intervals than within pre-stimulation epochs. The mean patient Fisher z contrast was -0.0888. Its 95% patient bootstrap interval was -0.2616 to +0.0592. The exact two-sided sign-flip test gave p = 0.3361. Twelve patients had negative contrasts and nine had positive contrasts. Shorter windows changed the mean direction. Unequal time gaps and no sham condition limit causal claims. This is a new analysis of a reused sample. It is not an independent patient replication. The package preserves code, voltage epochs, metadata, source hashes, tables, figures, and reproduction instructions. All 35 complete raw files passed fresh hash checks. Direct reconstruction matched all 4,417,600 saved voltage samples exactly. Independent numerical checks and two full repeat runs reproduced the result.

SEEG · intracranial EEG · beta power · rank agreement · negative motor response · sign-flip test · patient bootstrap

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References

2
  1. usesSEEG windows of 2 seconds showed no clear beta phase contrast after stimulation with negative motor responses in 21 patients with epilepsy sci:sha256:ac9fb257c1c3b2137901e5b3e1f100b1ff732413d927ad648f418a17434de9b6

    We reused the preserved 35 voltage epoch archives, source metadata, pinned source hashes, and raw retrieval and reconstruction code. We calculated a new endpoint based on ranks of channel beta powers. We independently checked the numerical result and freshly reconstructed all source epochs.

  2. usesdoi:10.18112/openneuro.ds006519.v1.0.0

    The analysis used all 35 released recordings from OpenNeuro ds006519 version 1.0.0. The package preserves the fixed source metadata, hashes, and retrieval recipe.

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