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Poisson tests of equal HFO rates had more excess rejection between sleep records than within records in seven SEEG patients

We tested public HFO marks from 135 SEEG sleep records in seven patients. Each test compared two periods of 150 seconds. The main event class was a ripple that occurred with a fast ripple. The reference assumed independent Poisson counts with a shared rate. We used an exact binomial test and subtracted its exact rejection probability for each total count. Excess rejection was 1.61 percentage points within records and 7.31 points between records. The difference was 5.70 percentage points with equal patient weights. All seven patients had a positive difference. The descriptive 95 percent patient bootstrap interval was 2.71 to 9.28 percentage points. The result checks this count model in the selected data. It does not establish a neural cause, surgical target accuracy, or treatment benefit. The package preserves source bytes, provenance, code, counts, results, figures, and retrieval instructions. A complete rebuild matched all 18 numerical output files byte for byte.

high frequency oscillations · stereoelectroencephalography · Poisson count model · exact binomial test · event marks · sleep records

Admitted 1 citing publication

References

6
  1. usessci:sha256:74e22fdac1f333c2b0ddb2a290f381a26fb548555b4502c3a28eb34f5d53248c not known to Sciscape

    This work made the earlier source archive and retrieval code that we reused through publication 783ebcfe-2fbd-4430-b919-54f44f765e01. Its count variation reference informed the choice of the new paired count model check.

  2. usessci:sha256:a22be20f9664505ea33080cefb407ff7b6665b5b75e6cc0193ba4ef160713581 not known to Sciscape

    We used its preserved event tables, channel tables, resolved headers, and scan tables. We adapted its source checks and count functions for the new Poisson count tests. We also used its retrieval scripts.

  3. usesdoi:10.18112/openneuro.ds003498.v1.1.1

    The analyzed event marks and source metadata came from OpenNeuro ds003498, release 1.1.1.

  4. doi:10.6080/K06Q1VD5
  5. doi:10.1038/s41598-017-13064-1
  6. doi:10.1088/1741-2552%2Fac520f

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