Under the source pulse layout, anchored mean subtraction after pulses raised pre-pulse phase locking in five SEEG control files for a centered 4–10 Hz filter

We tested whether voltage after stimulation can change an offline phase score before stimulation. We used the first 120 windows in each of nine public SEEG files from seven people. Five control files formed the main sample. We fitted a mean curve on 58 early windows. We subtracted the curve only after the candidate pulse in 60 later windows. The curve had a fixed baseline anchor. All stored voltage before the pulse stayed identical. A centered 4–10 Hz filter measured phase 20 ms before the pulse. Mean absolute phase change was 18.81 degrees in the five control files. Mean phase locking rose from 0.111 to 0.283. All five files showed an increase. The planned contrast compared pulse locking loss with loss at an earlier baseline. Its mean was −0.078, with descriptive 95% person bootstrap limits of −0.222 and 0.086. Thus the test did not show excess locking loss at pulses. Without the anchor, the contrast changed sign. The edit measures sensitivity to later input. It does not recover true neural phase or test a live device. The pulse layout follows source code because event markers are absent. The package contains input samples, code, source records, window scores, and three figures.

phase locking · signal processing · stimulation · SEEG · centered filter · phase sensitivity