Mean HFO order loss exceeded a reference with independent uniform event times and fixed counts in 106 SEEG sleep records
We measured the change in HFO rate order between two 150-second halves of public SEEG sleep records. We used OpenNeuro ds003498 version 1.1.1. The primary test used overlapping ripple and fast ripple marks on bipolar pairs with at least 20 marks per record. It included 106 records and 591 pair comparisons from eight patients with temporal lobe epilepsy. A strict order inversion had loss 1. A tie had loss 0.5. Agreement had loss 0. The mean loss, with equal weight for each patient, was 0.340. The exact reference mean was 0.253 under independent uniform event times with each full count fixed. The difference was 0.087. Its descriptive 95% patient bootstrap interval was -0.016 to 0.213. Six patients had positive differences, but two large differences drove much of the cohort mean. An added simulation check placed the observed score above all 20,000 model draws. This check applies to the fixed records and the model assumptions. It does not establish a population effect. The package provides the exact reference method, all planned checks, source marks and metadata, public retrieval recipes, code, figures, and an exact offline repeat. All 1,123 source files passed a fresh public source check. The study measures released marks. It does not test surgical outcomes.
high-frequency oscillations · SEEG · sleep · event timing · order loss · conditional reference · epilepsy · neuroscience
References
8- usessci:sha256:07021ce84951757b7a1768d453d2a5f1c95c7b55a4a53b0d640e3a80ad5de8a2 not known to Sciscape
We used its onset coincidence report to specify the scope of our no-shared-contact check. Our check measures rate order. It does not measure coincident onsets or establish separate sources. We read the report after the planned endpoints.
- usessci:sha256:74e22fdac1f333c2b0ddb2a290f381a26fb548555b4502c3a28eb34f5d53248c not known to Sciscape
We used the preserved ds003498 version 1.1.1 inputs and its verified input parser. These inputs enabled the new within-record order score and its fixed-count reference.
- usessci:sha256:a22be20f9664505ea33080cefb407ff7b6665b5b75e6cc0193ba4ef160713581 not known to Sciscape
We used its rate-list agreement report to specify the scope of our within-record score. Our score does not compare lists across records. We read it after the planned endpoints. The reports use overlapping source data.
- supersedesHFO mark order loss exceeded a fixed-count reference in 106 SEEG sleep records, with an interval that included zero sci:sha256:ad543b397cb6d4f05cce7ae95e3a04f8845fb2b65a0a752de632676599e613fa
This version uses a shorter title for the requested writing standard. It adds a version record and the first archive verification. It preserves the same source inputs, scientific code, and results.
- usesMean top overlapping HFO pair agreement was 3.3 percentage points below a conditional independent event model in 131 sleep SEEG records from eight patients sci:sha256:3476f900b125550daf85a57bf366f145d09adf243d15bf4c4b8a918d717c00de
We used its top-pair agreement report to specify how our all-pair order loss differs from top-pair selection. We read it after the planned endpoints. The reports use overlapping source data.
- usesdoi:10.18112/openneuro.ds003498.v1.1.1
Source events and metadata were taken from OpenNeuro ds003498 version 1.1.1, pinned in this package to Git commit d5aa5a24f3d4a8d49964fc88488aefa2b4dd9e44.
- doi:10.6080/K06Q1VD5
- supportsdoi:10.1038/s41598-017-13064-1
Table 1 supplies the implant and cohort information used to identify the depth-only SEEG patients.
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