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A 3 dB alpha peak rule gave patient mean reference and time disagreement of 9.33 and 12.24 percent in 19 SEEG records

We tested whether reference change gave more alpha peak label disagreement than change to the next minute. We used all 19 patients and 2,070 contacts from a pinned public SEEG sample. The fixed rule required a local 8 to 13 Hz maximum at least 3 dB above a linear background. Patient mean disagreement was 9.33 percent across references and 12.24 percent across minutes. Mean reference minus time disagreement was -2.91 percentage points. The patient bootstrap 95 percent interval was -6.93 to -0.075 points. The planned exact sign flip test gave p = 0.0858 and did not reject zero at the 5 percent level. That test requires independent patient contrasts and sign symmetry under the null. A fixed quadratic background check reversed the mean direction. An added influence audit showed a large contribution from one patient. The evidence does not establish a stable general order of the two changes. The result concerns the stated label rule and short interictal records from patients with epilepsy. It does not identify the best reference or confirm neural oscillations. This is a new analysis of an existing cohort. We rebuilt all 19 spectrum files from pinned public signal ranges. All 1,912,680 density values matched exactly. Fresh processes also gave exact main result file matches. The package preserves the code, spectra, source receipts, metadata, results, figures, local plan, and repeat instructions.

stereo-electroencephalography · SEEG · alpha peak · spectral analysis · reference choice · time stability · binary labels · epilepsy

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References

6
  1. usesAlpha excess selection gave more test window excess than alpha power selection in 19 SEEG records with an average reference sci:sha256:fbe93f72b2b5b6d83ae04bbdd3e55a7776af4f7b40c3da5101c3aeaa095ef7cf

    This study uses all 19 spectrum arrays, the raw validation fixture, the alpha peak rule, and the metadata and code from this parent. It tests a new binary label comparison in the same cohort.

  2. usesReference choice reduced mean 80 to 150 Hz rank agreement more than time change in 19 public SEEG records sci:sha256:16d6a5e5126b007f6f6be4f042d829df32ccd751f41bcfda4c9b9a3f5a80fce2

    This study uses the original patient selection, reference and time design, EDF helper, and pinned public signal range hashes. These inputs support the full public source rebuild.

  3. usesdoi:10.18112/openneuro.ds003876.v1.0.2

    This is the recorded version-specific DOI for the OpenNeuro dataset used in the analysis.

  4. doi:10.1016/j.neuroimage.2018.08.020

    Background work on SEEG reference choices cited in the publication.

  5. doi:10.1038/s41593-020-00744-x

    Background work on separating spectral peaks from aperiodic background; the publication states that its simple fit does not implement the full method.

  6. doi:10.1109/TAU.1967.1161901

    Source of the Welch spectral averaging method used in the analysis.

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