Bands set by early 7–13 Hz residual maxima retained a positive Alzheimer-control EEG contrast after age and gender adjustment in 65 processed ds004504 v1.0.9 recordings.
This audit tested a band choice in 36 Alzheimer and 29 control recordings from OpenNeuro ds004504 v1.0.9. Early 100-second posterior EEG samples set a 7–13 Hz residual maximum after a background fit. Late 100-second samples supplied scores. Both four-Hz and five-Hz bands shifted by that maximum minus 10 Hz. The common age and recorded gender model gave an Alzheimer versus control contrast of 0.2572 log10 units with fixed bands and 0.3000 with shifted bands. The main paired change was +0.0428 (95% person bootstrap interval -0.0457 to 0.1285). Its direction was uncertain; both score contrast intervals were above zero. The planned raw-maximum rule gave a change of 0.2606 (95% interval 0.0955 to 0.4129). The main analysis retained all 65 records. A separate comparison preserved the earlier peak-transfer study's exact 55-person sample. All 88 source hashes passed, and the extraction reproduced 167,200 prior band powers exactly. Independent formulas checked scores and 40,000 bootstrap group fits. An offline repeat reproduced all five result files byte for byte. The package preserves spectra for 88 persons, source provenance, code, plans, results, figures, and reproduction commands. The inference is limited to this processed cohort and these band rules. A frequency maximum need not be an alpha oscillator. No disease mechanism or external diagnosis performance is established.
EEG · Alzheimer disease · frequency bands · spectral power · band shift · person bootstrap
References
8- usesLog theta/alpha agreement was higher for 100-second than 10-second samples within 88 ds004504 v1.0.9 EEG recordings sci:sha256:42016de1c093d5655861aa1e4950809ff50a0d7e3e5b4f78b5b24887bb622428
This archive supplied the unchanged interval selector, extraction code, pinned source manifest, participant table, and band features. The fresh extraction used those inputs and reproduced all 167,200 archived absolute log10 band powers.
- usesThe adjusted theta/alpha EEG contrast remained in 55 selected ds004504 v1.0.9 Alzheimer and control participants after a fitted 6-13 Hz peak moved to 10 Hz with the log spectrum remainder fixed sci:sha256:b459bf4e8797de57fb08602f1c9b3511bba8ea5341390b40a77c7ef89c2758cc
The archived primary eligibility flags supplied the exact 27 Alzheimer and 28 control IDs for the separate context comparison. ID, group, age, and M fields were checked. Prior score values were not inputs. The main band-shift test retained all 65 records and tested a different mathematical operation.
- usesLinear age and gender models show higher EEG theta-to-alpha ratios in Alzheimer disease than controls in both 100-second ds004504 v1.0.9 samples sci:sha256:2244fd44453a171927142ebefe1a6874106c3142df58b30f9e92369ee339a852
The earlier result motivated the common age and recorded gender model. Its cohort findings were known before the new analysis. Its numerical estimates were not inputs to the new scores or contrasts.
- usesdoi:10.18112/openneuro.ds004504.v1.0.9
The analysis used the processed EEG derivatives in OpenNeuro ds004504 v1.0.9; the saved source manifest pins the analyzed files.
- usesdoi:10.3390/data8060095
This is the source dataset descriptor cited for the cohort and its supplied recording and preprocessing details.
- doi:10.1016/S1388-2457(03)00345-6
- doi:10.1109/ACCESS.2023.3294618
- doi:10.1007/s11571-026-10464-w
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