A linear contact number model reversed the mean SOZ contrast in spectral entropy change after marked seizure end in 30 SEEG patients

We measured spectral entropy before and after two marked seizures in 31 patients with public SEEG data. The source was OpenNeuro ds004100 version 1.1.3. The primary SOZ minus unmarked change contrast was -0.03494. Its patient bootstrap 95% interval was -0.06397 to -0.00637. The primary sign-flip p value was 0.0269. This test assumes independent patients and sign symmetry under the zero null. In the same 30 patients and 69 groups, group means gave -0.03740 and a linear contact number model gave +0.05420. Fifty-nine groups had separated contact number ranges for the two classes. The mean sign change shows model sensitivity. It does not establish a causal SOZ effect. The larger-group adjusted interval included zero. All retained input arrays matched a new source rebuild for all 31 patients. A separate decoder and direct Fourier calculation checked 32 spectra in two patients. The package preserves spectra, code, source versions, hashes, results, and repeat instructions.

spectral entropy · stereoelectroencephalography · seizure onset zone · epilepsy · contact number · model sensitivity