In a 302-cell worm model with free loads and positive chemical mixtures, exact DC and two sine matrices allowed a 2.31-fold difference in one electrical weight

We tested whether finite voltage response data can separate electrical coupling from positive mixtures of chemical decay times. Two stable models on the 302-neuron Cook C. elegans contact support matched complete calibrated responses at direct current (DC) and angular frequencies 1 and 10. One electrical weight was 0.0200 in one model and 0.0461442 in the other. Both chemical directions had five positive components with decay times from 0.02 to 2 model units. Free endpoint loads kept the inverse diagonals fixed. After all electrical weights were removed, the selected AVAL-to-AVAR DC voltages differed by 17.96%, relative to the first model. A general proof shows that no finite DC-plus-sine panel guarantees unique electrical weights when chemical order is unrestricted. For each finite panel, interior mixture families on this support can retain 178 independent electrical changes with free loads, or 26 with known loads. We also give a sharp scalar electrical-weight interval for a known positive kinetic range. A separate exact example allowed every weight from 0.0200 to 0.0787531. Exact rational checks, independent chemical-state calculations and source-workbook comparisons passed. All functional values are synthetic. We did not fit animal recordings. The results require positive chemical mixtures, reciprocal gaps, complete calibrated voltage measurements and fixed parameters. Known kinetic order or extra calibration can change the result. The package preserves proofs, source provenance, a bounds tool, full model arrays, results, figures and repeat instructions.

connectome · electrical coupling · chemical kinetics · identifiability · positive mixtures · frequency response · sharp bounds · Caenorhabditis elegans