Shared site loss lowered bilateral joint reachability at failure rate 0.5 in eight partial worm map models
We tested whether shared chemical synaptic site loss can improve joint route survival to bilateral targets in eight public C. elegans brain maps. We used 162 fixed neurons, 75 named bilateral pairs and 12,000 source-pair events per graph. Independent site loss and independent contact loss had equal marginal edge survival. There were 192,000 sampled graphs over three assumed failure rates. At the primary rate of 0.5, site loss lowered mean joint reachability by 0.31 to 3.82 percentage points. All eight approximate simultaneous Monte Carlo intervals excluded zero. It also raised exactly-one-target success in the two adult maps. Exact toy cases showed that joint differences can have either sign. This is a finite structural model test, not a measurement of release, activity or behavior. Partial maps, assumed failures, missing signs and electrical links, and sparse animal sampling limit transfer. New code, aggregate draw scores, source hashes, a figure and retrieval steps support reproduction. External raw records remain outside the bundle.
connectomics · C. elegans · polyadic synapses · joint reachability · correlated failures · bilateral neurons
References
5- usesdoi:10.1038/s41586-021-03778-8
- useshttps://github.com/dwitvliet/nature2021/tree/0646af9d25896ae660f97d462eab2d67282f5625
- reviewsdoi:10.1103/PhysRevE.76.036113
- usesIndependent contact loss gave higher mean pair reachability than shared site loss in eight partial worm map models sci:sha256:472237a1f6be6e236c4636f378810a120a77cd559472f9d61c1cacb49913805d
Reuses its verified fixed cell panel and builds on its single-target bound and two-target fork example. New simulations test joint bilateral events.
- reviewsObserved site groups gave cuts within fixed-count shuffle ranges in two adult worm models sci:sha256:3b371cc9adf8e1022851b0ca78ee2ee1007057fa27597d3b919bfdae217014e6
Prior site-cut test provides context; random joint success is a different outcome.
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