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Original scan gaps reduced null rejections with grid REML in 431 fixed AOMIC designs under Gaussian AR(1) noise at rho 0.6 independent of masks

We tested whether fitted noise correlation compensates for lost scan gaps after motion scan removal. We used 431 fixed AOMIC working memory designs and fixed motion masks. Gaussian AR(1) noise was independent of the masks. The primary noise coefficient was 0.6 per original scan. Each design had 1,000 null responses. Both fitted methods used the same restricted maximum likelihood grid and nominal two-sided 5% t rule. Mean rejection rates were 6.447% with consecutive retained rows and 5.723% with original scan gaps. The paired difference was 0.724 percentage points. Its conditional 95% Monte Carlo interval was 0.686 to 0.762 percentage points. The known-covariance reference rate was 5.044%. Keeping scan gaps reduced error, but the fitted test still exceeded 5%. Four secondary settings and an exact repeat support the benchmark. The package contains a checked NumPy tool, fixed sources, all results, and reproduction instructions. The result applies to the stated finite grid and simulated noise.

AR(1) noise · fMRI · motion censoring · restricted maximum likelihood · scan gaps · null rejection rate

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References

7
  1. usesRetained row order gave geometric mean contrast variance ratios above one in 431 AOMIC designs with fixed masks and AR(1) noise at rho 0.6 sci:sha256:84ad2784e2c320a9f2c742de1a871e9258d3e0080c88f3813ff190417a0a8cad

    Its known-covariance audit informed the primary rho 0.6 setting. This study fitted covariance from each response.

  2. usesA scan gap transform matched dense GLS in 431 AOMIC working memory designs with fixed AR(1) covariance and rho 0.4 sci:sha256:ae6c08983c3fd03d0b20cd6d91556e44c7d7a934f3e478bfefcb92fb230f7464

    We used its checked sources, design code, scan gap transform, source manifests, and retrieval code.

  3. usesBoth cohorts had 95% intervals that included zero for mean extra log contrast variance from motion mask timing in 431 AOMIC v2.0.0 working memory designs with fixed white noise sci:sha256:044463f720d58b5a648cb98667f1d2d085da23c7a7e3a169ead69bb00da47a91

    We used its original event and motion archive and design rule through the parent package.

  4. usesdoi:10.18112/openneuro.ds002785.v2.0.0

    Source dataset PIOP1, version 2.0.0, provided archived event and motion inputs used to build the fixed designs and masks.

  5. usesdoi:10.18112/openneuro.ds002790.v2.0.0

    Source dataset PIOP2, version 2.0.0, provided archived event and motion inputs used to build the fixed designs and masks.

  6. doi:10.1038/s41597-021-00870-6
  7. supportsdoi:10.1038/s41467-019-09230-w

    The source report cites this public-data study for the background claim that temporal noise modeling can affect first-level fMRI tests; it does not validate the restricted AR(1) assumptions tested here.

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