SEEG pair selection did not establish a positive later speech minus music contrast in 16 patients during one film

We tested a SEEG pair selection rule in 16 patients who watched one film. We used public OpenNeuro ds003688 data, version 1.0.7. We selected one contact pair per patient from six early film blocks. We tested the same pair in six later blocks. The main band was 65 to 115 Hz, with 98 to 102 Hz removed. The mean late speech minus music contrast was 0.299 dB. Its 95 percent t interval was -0.372 to 0.970 dB. The exact two-sided patient sign flip probability was 0.353729. 10 of 16 patients had a positive late contrast. The test did not establish a positive mean late contrast. It did not show that the effect was zero. Inference assumes independent patients and a sign-symmetric null. Film content and time can affect the contrast. The package stores selected signals, all candidate band features, source records, code, results, and repeat instructions.

stereoelectroencephalography · speech · music · high-frequency power · pair selection · clinical EEG · selection bias · within-subject validation