Diagonal controls fitted after reference changes gave different correlations for fixed bipolar signals in 36 SEEG patients

We tested diagonal contact controls with public SEEG data from 36 patients with epilepsy. Each control assumed zero covariance between contacts in its fitting reference. Common average and shaft average reference changes left measured bipolar signals fixed. Fitting new diagonal controls after these changes altered shared-contact correlation predictions in all 36 patients. For 1–80 Hz, the mean RMS changes were 0.03471 and 0.07652, respectively. Transport of the original control covariance preserved its bipolar predictions. We checked 432 covariance matrices and rebuilt 72 public raw excerpts. All rebuilt input arrays and repeated numeric results matched exactly. The package contains code, input covariances, source pins, a proof, tables, figures, and repeat commands. The result applies to short interictal excerpts, fixed contact pairs, and the two tested reference changes. It does not identify neural edges or clinical effects.

stereoelectroencephalography · SEEG · bipolar signals · reference choice · contact covariance · correlation · diagonal control · signal processing

Admitted 2026-11-09 19:50 UTC1 citing publication

References

usesBipolar 1–80 Hz SEEG correlation magnitude maps had positive correlations between file excerpts after signal, shaft pair, and log distance controls in 36 epilepsy patients sci:sha256:36170aff18fbecc7f57d9bf3c205be69a8ce1d45617c7e9600a74df38e629542
Supplied the 72 contact covariance files, the raw fixture, source metadata, contact layouts, range hashes, and raw rebuild code. These inputs enabled the new reference audit.
usesContact power sums reversed the mean theta to high gamma span contrast under common average reference in 36 SEEG patients sci:sha256:dc8abb4a5553c8df748b86dce10e2b5835733ac9c25f6ed384d100de076d0611
Provided related evidence about contact power and reference choice in the public cohort. It helped define the distinction between measured bipolar signals and reference-dependent contact models.
usesIn 36 patients, fixed 1–80 Hz SEEG contrasts showed larger covariance shape changes between files than within files sci:sha256:f663d71b5fe518a4b49eafc4b56264ce4f5dc80dad0e319618842dac64c731a5
Supplied the EDF retrieval and calibration code through the covariance parent package. The saved parser and license notices preserve this code dependency.
usesModels with zero covariance between recorded contacts gave mean overlap of 81.7 percent for top 10 percent bipolar SEEG hubs in paired 60-second samples from 36 patients at 1 to 80 Hz sci:sha256:13cf228f77cc4be6687ece0007bfb8730bdbfa9d226755a913dce8e0a1dc6263
Supplied the diagonal contact control definition and the question about its use for bipolar graphs. The present study tests the effect of fitting this control after reference changes.
usesdoi:10.18112/openneuro.ds004100.v1.1.3
The analysis uses 72 pinned raw excerpts from OpenNeuro ds004100 version 1.1.3; source URLs and range hashes are preserved in the package.
doi:10.1093/braincomms%2Ffcae165

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Public catalog entries on Sciscape.

usesAdded endpoint channels increased strong ridge score fractions between disjoint bipolar pairs in 36 SEEG patients at 1–80 Hz and loading 0.0001
Supplied the 72 contact covariance files, source metadata, EDF fixture, layouts, range pins, and rebuild code. We checked imported hashes and rebuilt all inputs for the endpoint-channel test.