The selected MNI count deficit within 25 ms of 10-second boundaries did not repeat in nine SEEG records

We tested whether released HFO marks had fewer onsets near regular file time boundaries. We used the first hour of 18 public SEEG sleep records from OpenNeuro ds005398 version 1.1.3. Nine patients formed the discovery group. We checked 78 detector, clock, and window choices; 33 met a fixed count rule. The selected choice was MNI, a 10-second clock, and a 25 ms half width. Its mean discovery patient contrast was -0.0791. The primary test used the second half hour in the other nine patients. It had 280 center marks and 257 nearby control marks at equal exposure. The mean patient contrast was 0.0408, with a 95 percent patient bootstrap interval from -0.0485 to 0.1425. The exact two-sided sign flip test gave p = 0.453125. The selected deficit did not repeat. This result does not prove that all timing bias is absent. The test assumes independent patients and symmetric effects under the null. The interval assumes exchangeable patients. The package has the fixed local plan, pinned source bytes, hashes, code, all results, figures, and offline instructions. All 94 source files or EDF headers matched fresh pinned public downloads. Separate checks passed, and an offline repeat matched all numerical outputs. No raw signal samples were analyzed.

stereoelectroencephalography · high-frequency oscillations · event timing · boundary effects · reproducibility