Baseline energy subtraction left pulse count effects in site ranks of subset mean SEEG scores at 19 contacts in five patients

We tested whether subtraction of baseline energy removes pulse count effects from a fixed SEEG response score. The source was OpenNeuro ds004457 version 1.0.2. The test used 19 contacts in five patients. At 6 mA, the mean site pair reversal rate was 15.7 percent between exact subset mean scores for two and eight pulses. Contacts had equal weight within each patient. Patients had equal weight. The descriptive patient bootstrap interval was 10.7 to 21.6 percent. The proof gives E_m = Delta U + Delta V/m. U is mean energy from distinct pulse pairs. V is sample variance across pulses. Delta means post minus pre. The distinct-pair correction removes the count term from the exact subset mean. A neural signal interpretation needs constant pulse means and zero cross-pulse error covariance. Shared artifacts can remain. We checked all waveform bins against hash-checked raw recordings. The package contains code, trial arrays, provenance, a proof, results, figures, and reproduction instructions.

stereo electroencephalography · electrical stimulation · pulse count · subset mean energy · site rank reversal · neural response measurement