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Common average reference gave negative full residual correlations and positive covariance pseudoinverse scores in independent contact controls from 36 SEEG patients

We compared full residual correlation with covariance pseudoinverse scores after common average reference. We used public SEEG data from 36 patients, with 72 runs and three frequency bands. The reference and the network used the same contacts. Full adjustment for all other channels gave residual correlation -1 when residual variance was positive. Independent contact controls kept the measured variances and removed cross-contact covariance. All 1,102,868 pair evaluations in the 1–80 Hz controls had positive covariance pseudoinverse scores. Small ridge values instead gave scores close to -1. We also checked a valid contrast interpretation of the pseudoinverse scores. The known rank and contrast results are not claimed as new theory. The contribution is a public SEEG benchmark and a reusable audit tool. All 72 raw prefixes passed their hash checks. All 432 rebuilt covariance matrices matched the archive bit for bit. The package preserves code, data, proofs, results, source records, and instructions. The controls do not estimate the fraction of real neural connections or support a clinical claim.

common average reference · SEEG · partial correlation · covariance pseudoinverse · ridge regularization · contact covariance · neural networks · rank deficiency · contrast association · reproducibility

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References

6
  1. usesFull partial correlation remains between disjoint bipolar channels within chains in independent contact controls from 36 SEEG patients sci:sha256:23d190482e6bb3cf7f70ae441ca5a265027502b817887a7a55812008167715b9

    The earlier bipolar partial-correlation study used independent contact controls in these 36 patients. Its reference-transform analysis motivated the separate comparison of CAR residual, pseudoinverse, and ridge measures. We cite its scope as prior work.

  2. usesEdges that share a contact are more common among the strongest 5 percent of 1–80 Hz bipolar SEEG correlations in 36 epilepsy patients sci:sha256:7dc3370736cdefb57323429971522e882b644b700faccfda51b916b3d865f58f

    We used the lossless contact covariance arrays, one signal block, selection rules, source decoder, filters, and pinned retrieval records. Fresh raw-prefix downloads reproduced all 432 covariance matrices bit for bit.

  3. doi:10.1093/braincomms%2Ffcae165
  4. doi:10.1007/s10548-019-00706-y
  5. doi:10.3389/fnins.2016.00123
  6. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The publication analyzes the HUP iEEG Epilepsy Dataset, ds004100 version 1.1.3. The saved external metadata match this exact version and record its DatasetDOI and CC0 license.

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