With equal patient weights, mean 30 second HFO count dispersion exceeded the uniform 1 second order reference in eight SEEG patients

We tested whether time order of one-second HFO counts raises 30 second count dispersion. We used public SEEG event marks from OpenNeuro ds003498 version 1.1.1. The primary set had 18,172 overlapping ripple and fast ripple starts in 387 pair and record combinations. It included 123 records from eight patients. Each record lasted 300 seconds. Pairs had equal weight within records. Records had equal weight within patients. Patients had equal weight in the cohort mean. Mean observed dispersion was 1.738. The exact uniform order reference mean was 1.070. Their difference was 0.668. The descriptive 95 percent patient resample interval was 0.077 to 1.395. Its interpretation assumes independent, exchangeable patients. Six patient differences were positive. Two patients supplied about 85 percent of the sum of differences. A stricter 50-mark requirement gave an interval that included zero. The study extends earlier work on the same cohort. It is exploratory and does not establish a neural cause or clinical benefit. The package includes a proof of the exact reference mean, a rational arithmetic tool, pinned source bytes, full results, and repeat instructions. An independent parser checked all 6486 pair results. The offline repeat matched all 21 numerical files. Fresh downloads matched all 1123 public source files.

high frequency oscillations · stereoelectroencephalography · count dispersion · event order · exact reference · epilepsy