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For common-average spectra at 20 to 100 Hz, inverse-frequency weights changed top contact sets in 12 of 19 SEEG records

Two fixed fit rules changed the top 10 percent contact set in 12 of 19 public SEEG records. We used 1,466 contacts from OpenNeuro ds003876 version 1.0.2. Each record supplied 120 seconds of common-average spectra. Fits used 20 to 100 Hz and excluded 57 to 63 Hz. We compared equal bin weights with 1/f weights. The equal patient mean slope change was -0.03220. Its 95 percent patient bootstrap interval was [-0.07103, +0.00345]. The exact sign flip test gave p = 0.12102 under patient independence and null sign symmetry. The primary test did not resolve a mean shift. Mean rank correlation was 0.97037. Mean top-set overlap was 0.86700. A saved residual audit accounts for each contact change by frequency. Exact power laws are invariant to these weights. The package preserves code, compact spectra, raw examples, source versions, hashes, results, and repeat instructions. The slopes do not isolate an aperiodic neural component. The study does not identify the better biological weight rule.

SEEG · intracranial EEG · spectral slope · frequency weighting · common average reference · contact ranking · epilepsy · weighted line fit · reproducibility

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References

6
  1. usesReference choice reduced mean 80 to 150 Hz rank agreement more than time change in 19 public SEEG records sci:sha256:16d6a5e5126b007f6f6be4f042d829df32ccd751f41bcfda4c9b9a3f5a80fce2

    This work supplied the source selection and EDF range reader reused through the direct parent. Those methods identify and retrieve the pinned public records.

  2. usesUnder patient independence and null sign symmetry, a test detected no mean 20–100 Hz slope change between averaging orders in 19 SEEG patients sci:sha256:7f859573f91c76431b4d88dcdc473ede2691d832bd77ffc8ebd66e1f2777ab8b

    We used its 19 archived SEEG spectrum files, original signal examples, source metadata, range receipts, and retrieval code. We changed the frequency weights in the line fit. We did not repeat its averaging-order hypothesis.

  3. usesWith independent patients and null sign symmetry, tests detected no HUP model SOZ AUC gain in 18 external SEEG patients sci:sha256:cacfcb73cf6624b3b7d324cad3700beeace003783bcff021dcba6e9769e783f7

    This work supplied the original 19 external spectrum files reused through the direct parent. We kept its contact pool and source intervals. We did not use its trained models.

  4. usesdoi:10.18112/openneuro.ds003876.v1.0.2

    The analyzed SEEG spectra and source metadata came from OpenNeuro ds003876 version 1.0.2.

  5. doi:10.1038/s41593-021-00901-w
  6. doi:10.1101/2021.10.15.464594

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