Mean bipolar SEEG slope rank agreement was lower between 30–100 Hz and 80–150 Hz fits than between recordings in 24-second samples from 35 HUP participants
We tested how the fitting range changes bipolar SEEG slope ranks. We used two public interictal recordings from each of 35 HUP participants in OpenNeuro ds004100 version 1.1.3. Each recording supplied three fixed 8-second sections. The feature was the negative straight-line slope of log power against log frequency. The fit ranges were 30 to 100 Hz and 80 to 150 Hz, with line harmonics excluded. Mean rank agreement was 0.685 between fitting ranges and 0.912 between recordings on the same pairs. The mean paired difference was 0.227, with a 95 percent participant bootstrap interval of 0.186 to 0.270. All 35 participants had positive differences. Planned checks retained this direction. The mean change in SOZ AUC was 0.062, with an interval of -0.010 to 0.135. The package preserves code, spectra, source versions, hashes, results, and instructions. All 70 spectra rebuilt exactly from pinned public source ranges. The result applies to these short samples and fit definitions. It does not establish a biological aperiodic measure or a preferred clinical range.
stereo-EEG · spectral slope · frequency range · rank agreement · seizure onset zone · measurement methods
References
4- usesAdjacent bipolar subtraction raises the mean 30–100 Hz SOZ slope contrast versus common average in matched pairs from 30-second sections in 35 HUP SEEG patients sci:sha256:071fcc058e31dc51079c34bbff2e4a090d0c0703817f0ef0e26cb6d9b684a2f4
Used its published description of the 30 to 100 Hz SEEG slope analysis to choose the lower fit range. The current analysis kept bipolar subtraction fixed and compared two fit ranges with two recordings. It used different short sections from the same HUP source cohort.
- usesMedian 80–150 Hz power rank agreement was lower between references than between recordings on matched pairs in 35 SEEG participants sci:sha256:eaad9a72db87113b65f5fda15f4c3043dc3463ac2f155c6b9d8b01404ec3ab9f
Used all 70 archived mean spectra, channel quality records, source metadata, pinned range receipts, and original retrieval and signal code. These files supplied the matched 35-participant dataset. The current study fitted new slopes and compared fitting ranges with recordings. A new public-source rebuild matched all 70 spectra exactly.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
The analysis used HUP iEEG Epilepsy Dataset ds004100 version 1.1.3 at the recorded Git commit da07f99bcd7a801f86191eceb2d35b0520c55d1a.
- doi:10.1038/s41593-020-00744-x
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