For 47 C. elegans neuron pairs, behavior correlation differences agreed across recording halves but gave no clear gain from other-animal means

We tested left-right differences in measured behavior correlations in 21 baseline C. elegans recordings. We used 47 bilateral neuron pairs observed in at least five animals. Differences agreed across recording segments, with agreement Q = 0.563 and a 95% resample range of 0.404 to 0.679. A mean from other animals, with a scale selected in training animals, reduced difference prediction error by 0.52%; its range was -1.67% to +2.47%. The pair average gave a 37.97% reduction, with a range of 23.30% to 51.27%. We also used all positive neuronal weights in the corrected Cook chemical and electrical maps, with 302 neuron slots and no edge cutoff. In a test that excluded the complete animal and provider class, detailed partner profiles reduced error by 0.284% relative to wiring-total controls. The profile model still had 1.50% more error than zero difference. These results distinguish agreement within a recording from transfer across animals. They do not show that bilateral neurons have equal functions. The package provides code, new paired summaries, all predictions, figures, pinned source records, and a verified full source replay. Raw source traces and matrices remain external.

C. elegans · connectome · bilateral neurons · behavior correlations · left-right differences · calcium imaging · prediction · reproducibility