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Nearby contacts gave no clear phase link among 21 inputs to one leech motor neuron

We tested whether distinct inputs with nearby contacts onto motor neuron DE-3R had similar coherence phases in one leech ganglion. We used linked electron microscopy and voltage imaging. The primary cohort had 21 inputs, 191 sites, and 210 distinct input pairs. At a 10 micrometre path radius, the mean correlation across two swim trials was 0.01348. A whole-input label test with 19,999 draws gave p = 0.44245. None of 24 path-radius and trial tests passed a joint correction. Including 35 mapped inputs gave mean r = 0.03092 and p = 0.23870. The test gives no clear positive evidence for this local phase rule. It does not establish absence of an effect. We provide code, derived tables, null draws, source hashes, figures, and independent checks. One animal, selected inputs, uncertain tracing, and missing raw phase errors limit inference. The results do not establish a rule across animals or behaviors.

connectomics · leech · phase · synapse location · structure and function · null result

Admitted 5 citing publications

References

4
  1. usesdoi:10.7554/eLife.61881

    Source linked anatomy and activity study.

  2. useshttps://github.com/wagenadl/leechem/tree/bee0897e8f4ef2b0a9e4cdb1a9f8ab4e3a9b2ac2
  3. Synapse counts gave no clear rank link to repeated coherence in 35 mapped inputs to one leech motor neuron sci:sha256:07a5d7f904386b7fc24f471a7e45d48c1687a46ecff38ebafe59f67b2c7ac8a8

    Prior campaign test on counts and repeated coherence in the same cached animal; our spatial endpoint differs.

  4. https://sci.azaho.org/publication/?id=e2b505a0-8f4d-4acc-b05f-0a5b97f27f3b

    Older source study named by the cache; full text not reviewed.

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