OpenNeuro ds004080’s CCEP derivative omits depth recordings, so its N1 table cannot answer SEEG questions
We audited whether the published N1 table in the OpenNeuro ds004080 CCEP derivative can compare surface (ECoG) and depth (SEEG) stimulation and recording in hybrid implants. Across 72 of 74 retrieved electrode tables, we identified 24 patients with 196 depth contacts across 30 runs. All 196 contacts appeared in channel lists, but none was a good recording channel. None of 91 depth-depth stimulation pairs had an N1 detection. For depth-to-surface units, the N1 rate was 0/5,106, compared with 10,199/81,664 (12.5%) for surface-to-surface units; a distance-matched comparison was negative in all 16 testable patients (exact sign-flip p = 3.1 × 10⁻⁵). These results describe coverage in the derivative, which did not evaluate depth contacts; they are not evidence that depth stimulation fails to evoke surface CCEPs. Surface-to-depth and depth-to-depth response comparisons are unavailable because depth contacts are absent as good recording channels. We did not inspect raw signals, and two electrode tables could not be retrieved, so a depth patient among those two subjects cannot be excluded. The archived code, unit table, audit outputs, input hashes, and figure support review and reproduction. SEEG questions require new N1 detection from the raw BrainVision files.
CCEP · ECoG · SEEG · intracranial EEG · N1 response · OpenNeuro · derivative audit · electrode coverage
References
3- usesOnly 10 of 34 audited OpenNeuro iEEG datasets had SEEG-typed channels; only two had SEEG in almost all subjects sci:sha256:acebaa9155a622379563f108b3dd9bd3621f3e2dfd2ead35cba6f376dd0b4ec4
This audit listed ds004080 as an OpenNeuro dataset with SEEG-typed channels in 25 subjects and no sci publication; we used it to select ds004080 and we now show that the dataset derivative does not evaluate these depth contacts.
- usesdoi:10.18112/openneuro.ds004080.v1.2.4
The audited CCEP derivative and electrode tables were retrieved from OpenNeuro ds004080; the dataset metadata records version 1.2.4 and a CC0 license.
- doi:10.1038/s41593-023-01272-0
Cited by
3 publicationsPublic catalog entries on Sciscape.
- usesIn 16 OpenNeuro ds004080 patients, depth-contact N1 probability decreased with distance, but prediction was weak
This audit showed that the ds004080 derivative has no good depth contacts. This finding is the reason we detected N1 again from the raw files.
- usesIn 16 patients, surface N1 latency decreased with age at ≥8 SD, while depth detections showed no decrease and were often not early N1
We used its finding that the ds004080 derivative has no depth contacts. This is the reason we used detections from the raw files and not the stored N1 table.
- usesIn 11 hybrid patients, depth contacts showed fewer negative N1 responses to surface pulses, while depth pulses evoked surface N1 at similar rates
This audit found that the ds004080 derivative N1 files did not evaluate depth contacts. We followed its advice and detected N1 on the raw signals for all ECoG and SEEG contacts.