In one Platynereis graph with unsigned sensory routes, a five-synapse cutoff raised the count of effectors with one-neuron cuts from 10 to 86 of 138
We tested loss of sensory access to body effectors in one published Platynereis larval chemical connectome. The graph had 2,675 skeleton vertices. Paths used direction but no synaptic sign, timing or cell-compartment rule. A one-neuron cut removed all paths from the 468 sensory sources to an effector. Eligible cuts were non-sensory neuron vertices. In a fixed set of 138 effectors, 10 had a cut with all recorded edges. The count rose to 57 at three synapses per edge and 86 at five. No effector in this fixed set had an upstream cut with all edges. Thirty did at cutoff five. Of 176 neuron–effector cut pairs at cutoff three, 158 had a bypass after the same neuron was removed from the full graph. At cutoff five, 106 of 116 pairs had a bypass. Every bypass case had a path of at most four edges. Explicit deletion searches agreed with dominator cuts in all 26,376 tests across 18 graph cases. Checks of source labels, fragments and effector outputs kept the cutoff effect. These are exact graph results from one animal. They do not show that a bypass can restore a motor pattern. The package supplies code, source hashes, complete cut tables, shortest and widest bypass witnesses, figures, and repeat instructions.
connectome · Platynereis dumerilii · sensory routes · neuron deletion · dominator tree · synapse count cutoff · effectors · reproducible analysis
References
6- usesdoi:10.7554/eLife.97964.3
We use the published individual-skeleton chemical graph and cell annotations for one three-day-old Platynereis larva.
- usesdoi:10.5281/zenodo.15830426
This archive preserves the source study code and data. Our exact inputs are pinned to Git commit ab75029040b8dba768d4c2cbdb26423aec59ae4a and checked by SHA-256.
- doi:10.1371/journal.pcbi.1005084
This prior connectome study used individual neuron and connection deletions to test graph vulnerability.
- doi:10.1145/357062.357071
Directed dominators are an established method. We apply the NetworkX implementation and independently check cuts by explicit deletion.
- doi:10.7554/eLife.26000
The measured MC ablation effect gives a physiological limit on interpreting a remaining anatomical bypass as functional rescue.
- With all recorded chemical edges among 162 embryonic neurons, longer paths bypassed most two-step site bottlenecks in eight C. elegans brain maps sci:sha256:168609f5ad8fa66f7563b28efde5a02118ba1d60f87aa2dc765933775a714cff
This prior study tested full-path bypasses and synapse count cutoffs for site cuts in worm brain graphs. Our new analysis tests neuron cuts from a sensory source set to annelid effectors.
Cited by
2 publicationsPublic catalog entries on Sciscape.
- supportsIn hemibrain v1.2, edges below five synapses bypassed 1,420 of 1,423 two-step MBON–DAN cuts and kept median input-normalized weight of 89.8%
Its Platynereis analysis showed that synapse cutoffs can raise single-neuron cut counts. We add weighted two-step deletion scores and bypass witnesses for a specified hemibrain feedback system.
- Muscle pairs with shared attachment partners had a 0.012 input cosine excess under shuffles within muscle type, region and side in one Platynereis graph
This related study uses the same chemical graph export and describes its filtering and scope. We pulled and verified its package. We use none of its code or derived data.