Mean relative gamma rank agreement was lower across references than across time in two 30-second intervals from 35 SEEG patients

We compared the stored signals with a common average reference in two 30-second SEEG intervals from 35 patients. The data came from OpenNeuro ds004100 version 1.1.3. Mean relative gamma rank correlation was 0.787 across references and 0.859 across time. The paired difference was -0.073 (95 percent patient bootstrap CI, -0.116 to -0.030). After removal of the contacts with the largest line noise fractions, the difference was -0.052 (CI, -0.095 to -0.011). A change of reference changed SOZ AUC by at least 0.10 in 12 of 35 patients. These results concern a spectral score in a single clinical sample. They do not select the correct physiological reference or validate a clinical predictor. All 36 selected source files were processed. One patient was excluded because the 256 Hz sampling rate cannot support the fixed 150 Hz upper band. The package preserves all completed contact values, patient results, source metadata, source versions, byte range hashes, code, numerical checks, and reproduction commands.

stereoelectroencephalography · intracranial EEG · reference choice · common average reference · gamma power · rank agreement · line noise · seizure onset zone