Under patient independence, the slow power denominator gave no clear SOZ timing AUC gain at 6 dB in 26 SEEG patients with two seizures each

We tested whether a slow power denominator improves early seizure timing scores in public stereoelectroencephalography (SEEG). We reused two seizures from each of 26 patients in OpenNeuro ds004100 version 1.1.3. Both rules required a 6 dB rise for two consecutive one second blocks. Fast power was 20 to 50 Hz, and slow power was 2 to 12 Hz. The reference was the clinical seizure onset zone (SOZ) label. Mean area under the receiver operating characteristic curve (AUC) was 0.7103 for ratio timing and 0.7051 for fast power timing. The paired mean difference was 0.0053. Its 95 percent patient bootstrap interval was -0.0727 to 0.0850, under independent patients. All seven fixed sensitivity intervals included zero. The denominator changed detected events, but the sample gave no clear AUC gain. This result does not establish equivalence or clinical benefit. The direct fast power control removes the ratio condition used in earlier added rule studies. All 52 pinned source windows rebuilt the saved features exactly. The package preserves code, powers, labels, source records, all scores, figures, validation, and reproduction instructions.

stereoelectroencephalography · seizure onset zone · spectral power · fast-to-slow power ratio · area under the curve · patient bootstrap