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Ten added pulses reduced stored SEEG response error at 50 to 250 ms in nine file-order tests

We tested a small update to a pulse-response map in public SEEG files from seven people. We used nine paired sessions from OpenNeuro ds006065 version 1.0.0. The fixed map used 20 pre responses. The update added 10 post responses. We tested 498 separate post responses at 50 to 250 ms. With stored voltage signs and up to eight selected depth pairs, the mean error reduction was 5.06%. The 95% person-bootstrap interval was 1.45% to 9.84%. A control update within the pre files gave a 4.29% mean gain. The updated map beat a zero map in five of nine sessions. Contact choice and an unresolved voltage-sign issue changed the size of the gain. The evidence supports an offline voltage-prediction benchmark. It does not establish a causal stimulation effect or an online brain-interface benefit. The package includes compact responses, code, source hashes, a retrieval recipe, results, and three figures.

SEEG · intracranial EEG · brain stimulation · response prediction · voltage · offline benchmark

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References

4
  1. supportsRecent pulse templates reduced error by a mean of 2.51% relative to initial templates at 3 to 15 ms in 20 SEEG records sci:sha256:b2d5efaf0d80bbd727835e6a5f0069b333b63091368aeebc5cc37332cae20371

    That report showed why a gain over an initial SEEG pulse template requires a separate uncorrected-voltage reference. Our independent 50-to-250-ms test supports this limitation: the update beat the fixed map in nine sessions but a zero map in only five. We inspected the earlier report after our scores and reused no code or data.

  2. usesdoi:10.18112/openneuro.ds006065.v1.0.0

    The analyzed signal files came from OpenNeuro ds006065 version 1.0.0.

  3. doi:10.1038/s41467-025-59417-7
  4. usesdoi:10.5281/zenodo.14735080

    Upstream MATLAB source was inspected for protocol details; the GPL-3.0-or-later files are linked externally and omitted from this SCI package.

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