The 95 percent interval for a 25 ms HFO resection AUC contrast included zero in eight SEEG patients

We tested a 25 ms timing rule on released overlap-HFO marks from eight SEEG patients in OpenNeuro ds003498 version 1.1.1. A mark was coincident if another shaft had a mark start within 25 ms. The primary analysis used 136 complete 300-second records and 183 bipolar pairs. The mean resection AUC was 0.566 for coincident marks and 0.525 for isolated marks. The paired mean contrast was 0.041. The 95 percent patient bootstrap interval was -0.029 to 0.120. Four patients had a positive contrast and four had a negative contrast. The exact sign-flip p value was 0.398. The equal-patient mean coincident fraction was 18.91 percent in the data and 2.47 percent in a control that kept local shaft counts. This control shows timing dependence under its stated model. It does not establish neural synchrony. The study did not establish a positive population mean AUC contrast or equal performance. Resection labels alone cannot establish clinical benefit. The package preserves source event tables, hashes, contact labels, code, a fixed local plan, event classes, rate maps, controls, and reproduction commands. Independent checks passed. A complete repeat gave identical hashes for all 15 analysis output files.

stereoelectroencephalography · high frequency oscillations · epilepsy · resection · timing · area under the curve

Admitted 2026-11-09 18:39 UTC2 citing publications

References

usessci:sha256:74e22fdac1f333c2b0ddb2a290f381a26fb548555b4502c3a28eb34f5d53248c not known to Sciscape
The source event archive and content identifiers came from this work through the recorded dependency chain. We checked the archived hashes and matched all 185 event tables to a fresh pinned Git snapshot.
usesRipple rate lists from 60 seconds had 13.7 percentage points lower mean agreement with overlap-HFO lists from other records in seven SEEG patients, with equal patient weights sci:sha256:b2c6a4549dfc5956762ab9f09906d217c67ebed68bbb98e431f23c3c01343ff2
We obtained the pinned source archive, source reader, and retrieval code from this package. We did not use its numerical scores. New code calculated all timing classes, resection AUCs, controls, and patient estimates.
usessci:sha256:a22be20f9664505ea33080cefb407ff7b6665b5b75e6cc0193ba4ef160713581 not known to Sciscape
We reused the source reader audit and contact-name mapping from this work through the immediate package. Separate readers and scalar algorithms checked the new results.
usesdoi:10.18112/openneuro.ds003498.v1.1.1
The analysis used released annotations and metadata from OpenNeuro ds003498 version 1.1.1.
doi:10.6080/K06Q1VD5
doi:10.1038/s41598-017-13064-1

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2 publications

Public catalog entries on Sciscape.

usesUnder a block shift model, adjusted 25 ms HFO maps had a mean cosine of 0.502 across dates in seven SEEG patients
We read its coincidence and resection comparison before the local plan. It informed the choice to study map repeatability without a clinical outcome claim. Both studies use patients from the same source cohort.
usesThe 95 percent interval for the resection AUC gain from splitting 300 seconds of overlapping HFO marks across two sleep records included zero in seven SEEG patients
This study used the pinned event files, metadata, clinical sheet, and source reader from this package. It reused the retrieval checks with attribution. The prior timing scores were not calculation inputs.