2 to 30 Hz normalization reversed the mean posterior theta eye-state contrast in 60 ds004148 v1.0.1 adults with a mean reference

We tested whether total power normalization changes the direction of a posterior EEG theta eye-state contrast. The main inputs were pinned OpenNeuro ds004148 v1.0.1 spectra from 60 adults. We used a 59-channel mean reference and 4 to 8 Hz theta. At visit 1, mean closed-minus-open absolute theta was +1.500 dB. Theta divided by 2 to 30 Hz power was -2.089 dB. The paired subject bootstrap intervals were +0.965 to +2.033 dB and -2.639 to -1.559 dB. Both used 97.5% coverage. An exact numerical split assigned 93.7% of the mean log denominator change to alpha. This allocation does not measure a neural cause. The reversal also appeared at two later visits and in five planned processing checks. The external check used 39 adults from ds007176 v1.0.1. Its first-visit means had the same directions, but both main intervals included zero. It did not confirm the reversal. CE and OE state meanings were assumed in that cohort. Fixed state order and unequal source cleaning limit physiological interpretation in the main cohort. The package preserves all 516 input spectra, source hashes and code, the local plan, new audit code, person contrasts, bootstrap draws, and figures. A fresh check reproduced four native records exactly. An offline rebuild reproduced every numerical output. The general absolute-relative effect is established. This work adds a scoped public-data test and a reusable denominator audit.

electroencephalography · theta power · relative power · spectral power · eye state · normalization · bootstrap · OpenNeuro

Admitted 2026-11-09 17:19 UTC2 citing publications

References

usesTotal power normalization reduces posterior alpha contrast between Alzheimer disease and control groups in ds004504 version 1.0.9 under a linear age and gender model sci:sha256:7398549287fd01cc48908b21dbdf6141edf9fe9ba47e3612e9d90b9a86d3fd0e
Its clinical power analysis provided prior use of absolute-relative accounting. We applied the established identity to paired eye-state spectra and preserved its mathematical interpretation.
uses2–30 Hz normalization lowered agreement across one month for posterior 8–13 Hz log EEG power in 60 ds004148 v1.0.1 adults with closed eyes and a mean reference from 59 channels sci:sha256:bedaa0bd2c9d4e6428ac7e7989a9b8ea1f23391c3114328c68a9ab33a200b565
Its test of total power normalization and alpha repeatability helped set the main 2 to 30 Hz denominator. We tested a different outcome: the direction of theta state contrasts.
usesThe alpha power share term was 70% of the mean 2–30 Hz posterior spectral entropy decrease with closed eyes in 60 adults under symmetric decomposition sci:sha256:fc68352740daf7a8e61fb30b48b649aa78ff743874cb5f1bdeaf36309ebdd28e
Its spectral entropy split used the mean of two component replacement orders. We used that allocation rule for the log total power denominator.
usesCE posterior alpha log power was more repeatable than the CE/OE log ratio across V0 and V1 in 38 ds007176 adults using 60-second segments sci:sha256:840e0d1801a45499fc18b519a47a306a84bcbb39b77919c26c1bac440ae6dc0b
We used its 156 pinned window spectra, extraction code, and native manifests for the external ds007176 check. We retained its 39-person selection and stated the CE/OE assumption.
usessci:sha256:eb6da8fdd843c3b66dd19edef3df5eb85f888448f106108e611352a1c6388159 not known to Sciscape
We used its 360 pinned window spectra, source extraction code, and native manifests for 60 ds004148 adults. We tested a theta state contrast instead of alpha repeatability.
usesdoi:10.18112/openneuro.ds004148.v1.0.1
Version-specific source dataset used for the main cohort.
usesdoi:10.18112/openneuro.ds007176.v1.0.1
Version-specific source dataset used for the external check.
doi:10.1038/s41597-022-01607-9
doi:10.1016/j.bspc.2026.109484

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usesDivision by 2–30 Hz power changed mean posterior theta–alpha log power correlation from positive to negative in repeated closed-eye EEG from 60 adults
Its theta eye-state contrast study supplied prior evidence of a denominator effect in this cohort. The present outcome is the temporal relation between theta and alpha scores within a record.
usesAn added test found opposite eye-state coordination contrasts after panel mean removal in 101 EEG volunteers and 47 fMRI adults under Student assumptions
Motivates an explicit audit of analysis transformations. Its normalization test uses other cohorts and a different EEG endpoint; its neural data and code are not reused.