Reference choice changed absolute beta power ranks more than runs in 36 SEEG patients with inferred neighbors

We compared common average and local Laplacian references in OpenNeuro ds004100 version 1.1.3. Neighbors were inferred from contact names. We used the first 30 seconds of two supplied interictal recordings from each of 36 patients marked SEEG. Both references used the same 3,183 central contacts. Mean rank correlation was 0.959 between runs and 0.790 between references. The paired patient difference was 0.168, with a bootstrap 95% interval of 0.144 to 0.195. All 36 patients had positive differences. The result remained positive with relative power, median spectra, shorter samples, and a template coordinate screen. Independent SciPy checks reproduced the primary correlations. The package contains code, contact features, source metadata, figures, and pinned retrieval ranges. The original reference and time between runs are unknown. The result does not select a clinical reference.

stereo-electroencephalography · SEEG · EEG referencing · common average reference · local Laplacian · beta power · rank correlation · signal processing