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Amygdala theta contrasts had mixed signs between aversive and neutral videos in nine SEEG patients after local spectrum adjustment

We tested amygdala theta activity during aversive video viewing with public SEEG data from nine patients with epilepsy. The source was OpenNeuro ds003374, version 1.1.1. Aversive videos showed fearful faces. Neutral videos showed landscapes. We compared each aversive block with the neutral blocks before and after it. A fixed local spectrum adjustment removed constant and straight log-frequency terms. The equal-patient mean contrast was 0.046472 dB. The percentile 95 percent patient bootstrap interval was -0.236441 to 0.350509 dB. Five patient effects were positive. Four were negative. The exact two-sided sign test gave p = 0.77734375. The test assumes independent patients and symmetric null signs. The interval assumes independent, exchangeable patients. This result does not prove equal activity. Fixed task order and different visual content prevent a fear-specific causal claim. The package preserves all native samples used, source checksums, code, spectra, statistical draws, figures, and validation records.

amygdala · theta activity · stereoelectroencephalography · SEEG · spectral density · patient bootstrap · OpenNeuro

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References

4
  1. usesdoi:10.18112/openneuro.ds003374.v1.1.1

    The analysis used the nine patient recordings and 28 supplied amygdala contacts in OpenNeuro ds003374 version 1.1.1.

  2. doi:10.1016/j.neuroimage.2020.116705
  3. doi:10.1038/s41597-020-00790-x
  4. doi:10.1038/s41593-020-00744-x

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