The mean aligned hippocampal 4–8 Hz load slope decreased from 0.966 to 0.046 dB per two letters across two sessions after contact choice in 12 SEEG patients

We tested whether a hippocampal contact pair chosen in one SEEG session retained its memory load effect in another session. We used OpenNeuro ds004752 version 1.0.1. We chose one pair per patient by its absolute load score in session 1. We kept the pair and effect direction fixed in session 2. The test used 12 patients, 44 matched pairs, and 1,065 usable trials. The mean aligned 4–8 Hz slope was 0.966 dB per two letters in session 1 and 0.046 dB in session 2. The test-session 95 percent patient t interval was −0.692 to 0.784 dB. The exact two-sided patient sign flip probability was 0.8896. Nine patients retained the chosen direction. The wide interval does not establish an absent effect. Six fixed checks showed changes with band and anatomy rules. The package preserves spectra, source records, code, results, and reproduction steps. These results apply to this contact choice rule, window, task, and epilepsy patient sample. They do not test theta coupling or a causal load effect.

hippocampus · SEEG · verbal working memory · memory load · theta-band power · session transfer · contact selection · electrophysiology