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Half-hour STE HFO maps had mixed excess distances under five-minute block exchange in 18 SEEG records

We tested time order in HFO channel maps from the first hour of 18 public SEEG sleep records. We used released STE marks from OpenNeuro ds005398 version 1.1.3. We compared consecutive half-hours with all 924 balanced allocations of twelve five-minute count blocks. The reference assumes exchangeable blocks and independent allocation across patients. Mean squared Hellinger distance was 0.1282 for consecutive halves and 0.1015 under block exchange. Mean excess was 0.0267. Eight of 18 patients had positive excess. A descriptive patient bootstrap interval was -0.0002 to 0.0588. The cohort tail estimate was 0.0463 with five-minute blocks and 0.0809 with ten-minute blocks. No STE patient tail passed Holm correction across 18 patients. These data show mixed effects and sensitivity to the reference. The package gives pinned public inputs, exact patient reference arrays, source code, figures, and a verified offline repeat. This study tests released marks. It does not establish a change in the biological HFO source.

high-frequency oscillations · stereoelectroencephalography · HFO maps · block exchange · squared Hellinger distance · temporal variability

Admitted 1 citing publication

References

5
  1. usesIn the first hour of 18 SEEG sleep records, 30-minute STE HFO maps had higher expected top 20% channel agreement than 5-minute maps sci:sha256:4d9fd5f1eaa1c005c1d288b2e596ac25540bdc558e18948e96c492be41759f09

    Its sample-length result in the same 18 records motivated the question. We tested the consecutive half-hour split against balanced block allocations.

  2. usesDuration weighting changed STE channel lists without a clear SOZ rank gain in 18 SEEG sleep records sci:sha256:085db5636d91d444b808e954f5729e3ef67b41e10aa238a106e0bd54578c4a24

    We used its archived public event files, pinned manifest, and retrieval code. We added an independent count parser and a block exchange test.

  3. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    Source event marks and channel metadata were analyzed from OpenNeuro ds005398 version 1.1.3.

  4. supportsdoi:10.1038/s41467-018-04549-2

    This paper supplies the reported prior evidence for temporal variation in HFO source locations.

  5. doi:10.1111/epi.18545

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