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Three quality filters increase the mean LGd minus VISp median firing rate difference in 30 mouse sessions.

In 30 mouse recording sessions, three quality filters increased the mean LGd minus VISp median firing-rate difference from 4.641771 Hz to 8.433269 Hz. The mean paired change was 3.791499 Hz (95% session-bootstrap interval 1.230817 to 7.633059). A planned check requiring at least five retained units per region reduced the estimate to 1.251400 Hz across 27 sessions (interval 0.729043 to 1.882380). Three sessions with only 1, 4, and 2 retained LGd units had large paired changes. These results describe selection in complete-session Allen metadata; they do not establish the firing rates of all neurons, identify a biological cause, or validate the quality metrics against ground truth. The source is a live Allen warehouse snapshot retrieved on 2026-10-09, not an immutable release. The analysis used metadata only, not spike archives.

firing rate · unit quality · visual cortex · LGd · VISp · Allen Brain Observatory · Neuropixels · session bootstrap

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  1. doi:10.1038/s41586-020-03171-x
  2. doi:10.1371/journal.pcbi.1012355

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