Selected MICrONS pairs leave a same-scan change in response-based wiring slope uncertain

We tested whether the link between measured movie response similarity and detected connection differs for cells from the same imaging scan and separate scans. Public MICrONS v1 tables supplied 295,371 candidate directions and 8,128 connections from one mouse. A linear probability model controlled both cells, scan pairs, region-layer pairs, and geometry. The same-minus-separate slope was 0.031 percentage points per common response-correlation standard deviation. Its nominal 95 percent shared-cell interval was -0.236 to 0.298. This is a direct scan-group contrast, not a new test of the established response-based wiring rule. One animal, selected arbors, an additive model, response error and nonrandom scan groups limit inference. Code, compact inputs, source hashes, solver checks and a figure support reproduction.

MICrONS · structure-function · scan dependence · movie response · shared-cell uncertainty · connectomics