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Adding five spectrum bands did not establish a SOZ mark AUC gain over contact numbers within contact name groups in 30-second SEEG from 18 external patients after HUP training

We fitted fixed models to 30-second SEEG from 31 HUP patients. We tested the models in 18 patients from two other sites. Mean AUC within contact name groups was 0.799 for bands and contact numbers. It was 0.770 for contact numbers alone. The paired change was 0.029. Its patient bootstrap 95 percent interval was -0.026 to 0.094. The exact two-sided sign-flip probability was 0.4102. The interval includes zero. The primary test does not establish a gain. The test ranks source SOZ marks. Unmarked target contacts have an unspecified source label. This result does not test treatment or normal tissue.

SEEG · epilepsy · seizure onset zone · spectral power · AUC · external validation · contact number

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References

5
  1. usesIn 30-second HUP SEEG samples, reference changes reduced mean 30–100 Hz slope rank agreement more than run changes sci:sha256:b9c7b4646dba303292f492835f91dbb8026d4f35fcce938519d1d3fa6bcbff63

    This archive supplied the original HUP common average spectra and EDF reader. Fresh public downloads checked all 62 source ranges and spectra.

  2. usesReference choice reduced mean 80 to 150 Hz rank agreement more than time change in 19 public SEEG records sci:sha256:16d6a5e5126b007f6f6be4f042d829df32ccd751f41bcfda4c9b9a3f5a80fce2

    This method supplied the fixed 19-record external list, source metadata, EDF object versions, and retrieval functions. New public ranges were retrieved for this test.

  3. usesFive spectral bands increased mean AUROC for SOZ labels beyond contact numbers in patient holdout tests of 30-second SEEG from 31 patients sci:sha256:877d1804af7740752f55814573a3207445a9f8d0161adbfae430e71a10695bfc

    This method supplied the fixed 31-patient HUP cohort, 2879 source feature rows, five spectrum bands, and contact number control.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    HUP training data, version 1.1.3.

  5. usesdoi:10.18112/openneuro.ds003876.v1.0.2

    Selected external test data, version 1.0.2.

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