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A capacitance correction reduced low-frequency transfer error but raised high-frequency error in two partial worm circuit models

We tested static circuit reduction and a first-order capacitance correction in passive models of two partial adult worm electrical maps. The graphs had 145 and 147 neurons. Thirty random half-observed masks were tested per map. With unit capacitance, leak 0.1 and angular frequency 0.1 in model units, the correction reduced median full transfer error from 9.57% to 1.75% and from 8.61% to 1.82%. It improved all 60 masks. At frequency 1 it raised error in all 60 masks. We give a sufficient continuous frequency band for a chosen full-matrix error limit and prove a high-frequency failure limit. Full-network calculations and 100 random-network tests checked the code. Counts are not measured conductances. Partial annotation, passive dynamics, assumed cell parameters and arbitrary time units prevent a claim about measured neuronal responses. The package includes a proof, graph arrays, masks, source hashes, code and all 6600 model cases.

Kron reduction · hidden neurons · electrical connectome · capacitance · frequency response · error bound · C. elegans

Admitted 2 citing publications

References

10
  1. doi:10.1109/TCSI.2012.2215780
  2. doi:10.48550/arXiv.1207.0563
  3. doi:10.48550/arXiv.2203.12084
  4. reviewsKron reduction held less activity variance than neuron deletion in 40 worms with a fixed Cook head graph sci:sha256:1bb75dac892cdb1d1ff3efdc7dcbf81bd4604726bfeacf39ca08e56f204c2d94

    Prior static spatial-mode test motivates a separate dynamic transfer benchmark; no numerical evidence reused.

  5. reviewsHidden relays with positive capacitance match direct transfer within 5% on 0-100 Hz in 31 passive models from Allen data sci:sha256:e156573e0e451055403d28de7d9429cf8100fb4753a73668247e91e9fbf0da6e

    Prior finite-band hidden-relay study; this work tests reduction error on larger worm maps.

  6. usesdoi:10.1038/s41586-021-03778-8
  7. usesdoi:10.1038/s41586-023-06683-4

    Uses only the atlas neuron label list, not the activity responses.

  8. useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_7.csv
  9. useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_8.csv
  10. useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/funatlas.h5

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