The median shared late energy fraction was 2% in 18 hippocampal SEEG recordings under independent zero-mean trial noise

We tested a response measure in public SEEG data from seven patients. The data had 18 recordings and nine stimulation sessions. We used one hippocampal contact per patient, selected from the authors' code. The late window was 50 to 250 ms after each pulse. We estimated energy shared between pulses with a correction for trial variation. The estimate assumes independent trial noise with zero mean. The median shared fraction was 1.97%. It ranged from -0.97% to 44.28%. The condition medians were 16.60% for theta-timed stimulation and 1.11% for phase-blind stimulation. Processing checks gave medians from 0.70% to 2.77%. Two response measures gave different change directions in four sessions. Their shared-energy intervals all included zero. These results describe this dataset. They do not establish treatment effects. The package provides source hashes, selected-contact waveforms, code, results, and reproduction instructions.

SEEG · hippocampus · evoked potentials · shared energy · trial variation · signal analysis