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A fixed -10% hand response bound passed in 14 ECoG patients and 58 fMRI adults under Student mean assumptions

We tested hand and tongue responses at sites selected with separate data. Public human studies supplied ECoG and BOLD fMRI. A local rule fixed four shared claims. Input audits then corrected MRI development identities and excluded one repeated ECoG record. Corrected confirmation used 14 patients and 58 adults. At tongue-selected sites, mean N+0.1P was 15.003 electrical power points and 2.161 MRI source units. Their 95% person Student limits were [5.424,24.581] and [0.954,3.368]. P was positive in each study. The shared four-claim Holm p was 0.009788. Thus mean hand responses exceeded -10% of mean tongue responses under this assay and mean model. The reverse bound failed, Holm p=0.111181. Both shared decrease tests failed. The passing electrical bound interval crossed zero with median reference or preceding rest. This is not processing-independent neural generalization or evidence of absent inhibition. An audit found 18 exact repeated movement/rest pairs in one patient. A tested version URL also returned other subject IDs. All 124 final MRI files match version-tagged hashes. These are disclosed, corrected tests in reused public people, not an unchanged external preregistration. Cohorts, movements, coverage, baselines and signal filters differ. The package gives original code, source pins, nominal and corrected results, figures and repeat steps. Original neural arrays remain external.

human neuroscience · ECoG · fMRI · motor cortex · tongue · hand movement · negative BOLD · independent data · data provenance · exact duplication · response bound

Admitted 2 citing publications

References

11
  1. doi:10.1073/pnas.1119125109

    The reported negative motor homunculus motivates the response prediction.

  2. doi:10.1371/journal.pone.0215736

    This study supplies related evidence on negative motor BOLD and its limits.

  3. usesdoi:10.1523/JNEUROSCI.3886-06.2007

    This paper describes the original motor task and electrical signal methods.

  4. doi:10.1523/JNEUROSCI.0877-12.2012

    This study reports negative electrical responses under other task conditions.

  5. doi:10.1038/jcbfm.2013.97

    This study tests motor neurovascular coupling under a different movement design.

  6. After each response was centered across features, a fixed daily finger movement model gave positive mean alignment in six ECoG patients and six fMRI adults sci:sha256:d836cb0a0184e9c6b43c70e12190e39f69bf35d756f7b510b78af3eb1002d3a7

    This related SCI motor study informed person-level inference and checks of processing dependence. Its task and MRI data differ.

  7. usesdoi:10.1038/s41562-019-0678-3

    The public Stanford library supplies motor_basic.zip and its terms.

  8. usesdoi:10.1038/s41597-022-01644-4

    The data paper supplies the MRI task, cohort and source processing methods.

  9. usesdoi:10.18112/openneuro.ds004044.v2.0.3

    Version 2.0.3 supplies the six-run hand and tongue contrast maps.

  10. usesdoi:10.1038/nature18933

    The Glasser atlas defines the MRI area-4 mask and the broader sensory-motor check.

  11. A lower-bound search finds 24 duplicate recording pairs in 42 OpenNeuro SEEG datasets sci:sha256:aa378b71b7ae2ccb611fd7f55e63bb4cc14c73203c92baf10ffdcf669e6e85e1

    This prior survey documents duplicate intracranial recordings. Our audit tests repeated within-record movement/rest pairs.

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