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Scorer adjustment changes linear age estimates for N2 transitions to wake or N1 over eight hours in 153 Sleep-EDF nights

We tested age and N2 transitions to wake or N1 in 153 Sleep-EDF nights from 78 people. Source ages were 25 to 101. We used the first eight hours after lights off. The linear age model included sex, night, bout position, and sleep time. Without scorer codes, the odds ratio per ten years was 1.066 (95% interval: 1.027 to 1.106). With scorer codes, it was 1.000 (0.959 to 1.042). We used 2,000 bootstrap draws of people. A paired comparison supported a change between the model estimates. This does not prove scorer bias or no age effect. An age audit found eight conflicts in files from five people. The primary estimate changed little under two age checks. The package contains all source annotations, verified counts, code, hashes, and run instructions. A fresh download reproduced all 180 source, result, and figure files exactly. The result applies to the source labels, selected sample, and stated model.

sleep transitions · N2 sleep · sleep scoring · age · scorer adjustment · Sleep-EDF · logistic regression · bootstrap

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References

4
  1. usesdoi:10.13026/C2X676

    Sleep-EDF Expanded is the source dataset used for all 153 cassette hypnograms and the subject table; the exact source URLs and hashes are retained in original/provenance/sources.json.

  2. doi:10.1016/j.neurobiolaging.2012.05.018
  3. doi:10.1093/sleep%2Fzsx117
  4. doi:10.1038/s44360-026-00096-z

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