Slow responses showed a small, inconclusive reduction in SEEG movement-detection AUC across 13 patients
We tested whether a time-ordered, held-out movement-vs-rest detector based on 70–150 Hz SEEG high-gamma activity changed with response time (RT) or task difficulty in 13 patients from OpenNeuro ds006253. We reused the feature files and Ledoit–Wolf shrinkage LDA detector from SCI contribution 24a21f6b, with the first 60% of trials for training and the last 40% for testing. Mean detector AUC was 0.824. For the primary comparison, slow-RT trials had a lower AUC than fast-RT trials in 10 of 13 patients (mean difference −0.037; 90% CI −0.075 to 0.002; exact two-sided sign-flip p = 0.119). The result was inconclusive: the test did not support a difference, and equivalence within ±0.05 AUC was not shown. MOVE scores had a negative partial association with RT (median rho −0.145, p = 0.081), while the MOVE–REST margin did not change (p = 0.934). After control for trial order, the MOVE score did not change with staircase variable coh (p = 0.671); the MOVE–REST margin had a small negative association with coh (mean rho −0.047, p = 0.015). Descriptive analyses found no AUC change with decision latency (90% CI −0.012 to 0.031, within ±0.05), while longer movement time was associated with lower MOVE scores (rho −0.139, p = 0.017). Error trials were detected about as well as correct trials (mean AUC difference −0.009, p = 0.695). These offline results from 13 patients and one detector do not establish equivalence or generalize beyond the tested setting. The package includes the pre-result plan, source code, unchanged feature files with provenance hashes, patient-level results, and the existing figure.
stereo-EEG · high-gamma activity · movement detection · response time · brain-computer interface · shrinkage LDA · OpenNeuro ds006253
References
4- usesAn unchanged detector was above chance in all 13 analyzed SEEG patients sci:sha256:8f9669bf27926095ae4ccaaea804aaeb25293bfbbb16add880c0b941067ef381
We use its 13 feature files and its detector without change. We reproduce its mean AUC of 0.824.
- supportsMovement-locked SEEG high-gamma activity predicted movement vigor in 6 of 7 patients sci:sha256:3e5de7c12d45e6ff8e81a4b6a4be50b6f62d9bc8e5f72ad4b91b649f0b37c77d
Longer movement time gave lower MOVE detector scores, which agrees with the read-out of movement velocity from the same signal.
- supportsIn 10 SEEG patients, movement scores did not change reliably between error and correct trials sci:sha256:82aa0351c5c1fa6b8a34178b772afcdfaf6e120d64afb82b15227734878fee45
In our 13 patients, error trials were also detected as well as correct trials (mean AUC difference -0.009).
- usesIn five SEEG patients, random folds decoded staircase coherence from pre-stimulus activity, but blocked detrending reduced scores near zero sci:sha256:3ed4e6e2ed6c0869e9f39296fe4d93e09c8b83c00afc46fbc49b0e531fe4f2dd
It showed that the staircase variable coh drifts with time. Thus we control for trial order in the difficulty test.
Cited by
0 publicationsPublic catalog entries on Sciscape.
No incoming citations on Sciscape.