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q-bio.NC · Neurons and Cognition

100 ms shaft controls gave less mean HFO start excess within 50 ms than 30 s controls in 136 SEEG records

We tested how local count controls change the excess of close high-frequency oscillation starts across SEEG electrode shafts. We used OpenNeuro ds003498 version 1.1.1. The study included 136 sleep records from eight patients. There were 23,779 ripple marks that overlap fast ripples. An exploratory audit tested nine control block lengths and four block origins. Independent uniform shaft rotations retained each block count and cyclic pattern. The mean excess within 50 ms fell from 15.07 pairs per 100 marks with 30 s controls to 3.89 with 100 ms controls. Every close pair was retained in this comparison, including pairs across block boundaries. The 100 ms excess range over four origins was 3.89 to 4.01. The origin-zero descriptive 95% patient bootstrap interval was 1.61 to 6.08. The same-block rule gave exactly zero excess with 50 ms blocks because every possible within-block pair met the start limit. This is a loss of sensitivity, not evidence of independent timing. Related work already found close timing in this same cohort. The contribution is a checked comparison of control scale, block origin, and boundary pair selection. It does not establish neural coupling or clinical use. The package preserves code, source files, hashes, decision records, results, figures, and reproduction instructions. All 26 numerical result files matched an offline repeat.

high-frequency oscillations · stereoelectroencephalography · event timing · shaft controls · temporal resampling · control timescale · OpenNeuro ds003498

Admitted 1 citing publication

References

9
  1. supportssci:sha256:07021ce84951757b7a1768d453d2a5f1c95c7b55a4a53b0d640e3a80ad5de8a2 not known to Sciscape

    Both studies found excess HFO starts within 50 ms under stated local count controls in this same eight-patient cohort. This study used all 136 records, shaft structure, and different score weights. The shared source does not give independent biological replication.

  2. usessci:sha256:73e42f2543dcded2b2577ecbc89c09eac8e76acdb88dd38622ed338522d5588e not known to Sciscape

    This study already tested shaft shifts and finer control blocks in the same 136 records and 23,779 marks. Its result was read after our primary calculation. It helped motivate the later audit of nine scales and four origins at a 50 ms limit. We do not claim the first close-timing finding or the first grid-origin check.

  3. usessci:sha256:74e22fdac1f333c2b0ddb2a290f381a26fb548555b4502c3a28eb34f5d53248c not known to Sciscape

    This is the earlier source archive for the files reused through publication 783ebcfe-2fbd-4430-b919-54f44f765e01. The citation records source lineage. The new analysis used the same public cohort.

  4. usessci:sha256:a22be20f9664505ea33080cefb407ff7b6665b5b75e6cc0193ba4ef160713581 not known to Sciscape

    This archive supplied pinned source event files, metadata, manifests, and retrieval code. We checked source hashes and freshly retrieved all 136 primary event files. The previous rate results did not supply the new timing statistics.

  5. usessci:sha256:5b4b6422ce58c80fe96d5f589b10b790bd56a29c306916bda7fcbf1df9a8176c not known to Sciscape

    This study reported excess 50 ms timing with local rotations and the exact adjacent-block mean in the same cohort. It was read after our primary calculation. The follow-up audit uses this known boundary calculation to retain all close pairs across 36 grids, with actual partial edge lengths. No new exact-mean formula is claimed.

  6. usesdoi:10.18112/openneuro.ds003498.v1.1.1

    The analysis used HFO marks from OpenNeuro ds003498 version 1.1.1, pinned to Git commit d5aa5a24f3d4a8d49964fc88488aefa2b4dd9e44. The saved version metadata declares CC0.

  7. usesdoi:10.6080/K06Q1VD5

    The publication identifies CRCNS ieeg-1 as the original data source for the analyzed OpenNeuro cohort.

  8. supportsdoi:10.1038/s41598-017-13064-1

    Fedele and colleagues describe the source cohort, depth electrodes, sleep recordings, and HFO detector that produced the released marks used here.

  9. doi:10.1152/jn.00633.2011

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