An adult fMRI timescale map had negative rank correlations with iEEG after control for cortical hierarchy in two patient cohorts

We tested regional timescale order in human iEEG and three released fMRI group maps. Two separate patient studies supplied electrical estimates. A common cortical atlas matched recording sites to fMRI parcels. The adult map gave negative correlations after control for cortical hierarchy. Mean correlation was -0.162 in 71 MNI patients. Its conditional 95% interval was -0.253 to -0.068. The mean was -0.261 in 233 RAM patients, with interval -0.292 to -0.229. Holm spatial p values were 0.0486 and 0.0040 across four adult tests. Simulation error made the MNI threshold result uncertain. The planned prediction of positive transfer failed. Position control reduced the MNI mean to -0.027, with an interval that included zero. Youth maps gave positive means. A strict RAM cortical-label subset also failed the spatial test. The inverse finding applies to one adult group map under the stated controls. It does not establish an inverse biological mechanism or individual fMRI agreement. The package preserves the plan, code, permitted inputs, results, three figures, source hashes, and numerical checks. A checked script retrieves an omitted MNI table whose redistribution terms remain unresolved.

human neuroscience · intracranial EEG · fMRI · timescale · spatial null · cross-modal generalization · negative results