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Bipolar SEEG pairs selected for low beta change before a response had a mean -0.050 dB contrast with other pairs 0.5 to 1.5 seconds after it in later trials from eight ds004473 patients

We tested whether sites with low beta change before a key press had greater beta change after it. We used public SEEG from OpenNeuro ds004473 version 1.0.1. We formed adjacent bipolar pairs. The first 40 trials per patient set the pair ranks. We selected the lowest ranked pairs within each shaft. The 20 percent count was rounded up. The last 40 trials tested that selection. The primary window was 0.5 to 1.5 seconds after the response. The baseline was before fixation. The mean selected minus other contrast was -0.050 dB across eight equally weighted patients. Its 95 percent patient bootstrap interval was -0.152 to 0.055 dB. The exact two-sided patient sign-flip p value was 0.4531. The fixed primary test did not detect a contrast at the 0.05 level. The package preserves all 640 trial feature sets, mean spectra, source metadata, raw range hashes, 16 raw check ranges, source code, results, and repeat instructions. Separate test trials do not give independent patient replication. These data cannot establish a neural cause or clinical use.

stereo-electroencephalography · beta power · bipolar electrodes · response timing · patient-level inference · reproducibility

Admitted 1 citing publication

References

3
  1. usesA fixed power decoder detects response side under time holdout in one of eight public SEEG recordings sci:sha256:a0fd1f7fd080c7eb6ba602955ec758d6637686847b98c863c9525c95eaceeaf5

    We used the unchanged EDF reader, checked HTTP byte-range retrieval, event join, and adjacent bipolar pair rules from code/extract.py. We preserved that file as code/upstream_reader.py. The new analysis has a separate fixed site-selection question and uses new signal windows.

  2. usesThe mean contralateral minus ipsilateral beta change was 0.008 dB for one-second response windows at SEEG sites matched within 20 mm in eight ds004473 patients sci:sha256:67bbc4f3dde8dad5bfa0d87f49e9208f933ed0c13410f95876282312f67f6791

    We retrieved the source metadata, raw object records, and EDF reader through this package. Its response-window result led us to test separate windows before and after a response. We retrieved new raw ranges for the new features.

  3. usesdoi:10.18112/openneuro.ds004473.v1.0.1

    Source dataset for all eight SEEG recordings analyzed in this publication (OpenNeuro ds004473 version 1.0.1).

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