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With equal signal ranks, common phase controls raised expected event concentration in five SEEG patients and eight fMRI participants

We tested whether concentrated slow neural activity exceeds a Fourier phase reference in both SEEG and fMRI. The studies had separate cohorts and films. We excluded pilot people. The test used 200 frames, 16 signals and equal marginal ranks. A planned secondary comparison showed that common phases raised expected event concentration relative to independent phases by 6.45 percentage points in five SEEG patients and 8.94 points in eight fMRI participants. Subject resampling ranges were +2.09 to +12.13 and +8.14 to +9.70 points. The difference was positive in every person. This shared result concerns the control rule. The primary excess claim did not generalize. Excess was 6.72 points in SEEG (range +3.98 to +9.56, conditional p=0.001) and -0.12 points in fMRI (range -0.55 to +0.29, p=0.582). Planned sensitivity checks retained this pattern. Common phases preserve cross spectra before the final rank step, not after it. A check with exact cross spectra also failed to show positive fMRI excess. Small cohorts, unequal spatial samples, epilepsy, processing and films limit inference. The SEEG secondary sign test depends on the test family: Holm p=0.03125 within two secondary tests and 0.0625 across all four main tests. The package contains code, compact data, source checks, all reference values, figures and repeat steps. It supports no causal claim.

SEEG · fMRI · cofluctuation · phase randomization · cross spectrum · movie watching · independent cohorts · reproducibility

Admitted 5 citing publications

References

14
  1. usesCortical fMRI patterns matched 8 of 10 people per direction across two movies after movie mean removal in ds006192 v1.0.0 sci:sha256:fe30461322d397906ebbe5f961169c9bfdf8cf3c87504a69f95649ec22d51b88

    The verified publication supplied the standard PAFIN regional source tables, source manifest and processing records. We use the same people for a different question; this is not an independent replication of its person-matching result.

  2. Removing circular shifts at distances of 1 to 10 rows gave 5.31% mean null rejection under independent phases with fixed spectra for 50 cortical pairs in 20 ds006192 movie fMRI runs sci:sha256:b4916aa5a4019cdf29b4216d04e39327008a472d2a59e1fa1cd814b75c412aae

    Its phase and autocorrelation audit on the same fMRI source helped motivate explicit reference checks. It does not confirm the present SEEG or event result.

  3. usesdoi:10.18112/openneuro.ds003688.v1.0.7

    Raw public clinical SEEG, channel status, events and provenance.

  4. usesdoi:10.1038/s41597-022-01173-0

    Source study, acquisition details, task and dataset attribution.

  5. usesdoi:10.18112/openneuro.ds006192.v1.0.0

    Released standard XCP-D regional fMRI derivatives.

  6. usesdoi:10.52294/001c.151820

    PAFIN study and source cohort description.

  7. doi:10.1073/pnas.2005531117

    Established high-amplitude edge cofluctuation analysis.

  8. doi:10.1016/j.neuroimage.2022.119476

    Showed that static covariance can account for common BOLD event properties.

  9. doi:10.1038/s41467-022-29775-7

    Mathematical account of edge energy and Gaussian covariance controls.

  10. doi:10.1016/j.neuroimage.2017.09.012

    Defines the limits of inference from phase references and non-rejection.

  11. usesdoi:10.1103/PhysRevLett.73.951

    Established multichannel common-phase Fourier reference method.

  12. usesdoi:10.1162/imag_a_00257

    Upstream XCP-D processing.

  13. usesdoi:10.1038/s41592-018-0235-4

    Upstream fMRIPrep processing.

  14. usesdoi:10.1093/cercor/bhx179

    Cortical parcellation underlying the 100 retained 4S156 cortical labels.

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