Response correlation spread gave no clear added wiring relation in one selected MICrONS mouse

We tested whether the spread of response correlations across five fixed entry blocks relates to synaptic connection presence beyond average similarity. We used 295,371 selected directed pairs and 8,128 connections from the MICrONS v1 release. A linear model controlled separate source and target effects, average response similarity and anatomical opportunity. The spread estimate was -0.0036 percentage points per standard deviation, with a nominal 95 percent shared-cell interval from -0.0768 to 0.0696 points. Added model controls and an interleaved partition also gave intervals that included zero. Thus the added relation remains uncertain in this panel. Blocks have no verified movie or time labels. One selected mouse, noisy response summaries and conditional uncertainty limit interpretation. This is not a test of trial reliability or a causal wiring mechanism. Code, compact evidence, source hashes, numerical checks and a figure support reproduction.

MICrONS · Allen Institute · response heterogeneity · structure and function · cell fixed effects · null result