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A 6 dB spectral rise rule gave a mean order score of 0.12 within label classes across two seizures in 18 SEEG patients

We tested whether a fixed spectral rise rule gave the same local order across two seizures in public SEEG from OpenNeuro ds004100 version 1.1.3. Both compared bipolar pairs had a rise in both seizures, the same clinical onset label, the same shaft, and no contact in common. Time ties stayed in the score. The 6 dB rule required two consecutive one-second blocks. The mean patient score was 0.124 in 18 of 26 source patients. Its 95% patient resampling interval was -0.086 to 0.318. The conditional upper-tail permutation p value was 0.07625. This test assumes that the joint time law permits separate time permutations within the selected groups. The primary result leaves substantial order uncertainty under that model. It does not show absent seizure spread. All planned checks are reported with their different selected samples. The package preserves the local plan, code, features, comparisons, draws, source identities, and repeat steps. All 52 fresh source ranges matched their archived hashes. Every source feature array and a separate analysis repeat matched exactly. This is an informed follow-up on a reused cohort, not an independent clinical replication.

stereoelectroencephalography · seizure onset · spectral rise · event order · repeatability · permutation test

Admitted 2 citing publications

References

4
  1. usesEarlier sustained 6 dB fast-to-slow power rises gave higher mean SOZ label AUC than rise occurrence within 20 seconds in two seizures from each of 26 SEEG patients sci:sha256:1df366118bf1962f80d9b6f86884a530dcc385bb9e87e576e76ccc40f50df7b0

    We reused its 26-patient feature package, pinned source metadata, and retrieval code. Its prior timing correlation informed the new within-label order question. We rebuilt all features from source bytes. The new comparison rule requires two detected rises, the same label, one shaft, and no common contact. The parent cohort is not an independent replication.

  2. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Analyzed source: HUP iEEG Epilepsy Dataset, OpenNeuro ds004100 version 1.1.3.

  3. doi:10.1093/brain%2Fawn111
  4. doi:10.3389/fneur.2025.1617317

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