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Pooled PCA retained more 1–80 Hz SEEG contrast variance on average than path PCA in separate records from 36 patients with training path power scales and a 20% component rule

We tested whether pooled principal component analysis (PCA) preserves more stereoelectroencephalography (SEEG) variance in a separate record than PCA fitted within each electrode path. Public inputs came from OpenNeuro ds004100 v1.1.3. The test used 36 patients and 72 interictal records. Both methods removed path means and used the same training path power scales. Each method kept the ceiling of 20% of the contrast dimensions. Path PCA used the best training rank allocation. For 1–80 Hz signals, mean retained test variance was 73.52% for pooled PCA and 68.76% for path PCA. The equal-patient gain was 4.76 percentage points. The 95% patient bootstrap interval was 3.79–5.86 points. The gain was positive in 35 patients. The interval assumes independent, exchangeable patients and holds fitted scores fixed. All planned secondary tests are reported. All 72 public raw excerpts were retrieved and hash-checked. Their rebuilt covariances matched exactly. Offline and fresh raw-data repeats each reproduced 79 analysis outputs exactly. The package preserves code, covariance inputs, fitted models, source versions, range hashes, results, and instructions. The gain concerns measured, scaled contrast variance. It does not identify neural sources or show a clinical benefit. The true time gap between files remains unverified.

principal component analysis · stereoelectroencephalography · SEEG · spatial filtering · variance retention · cross-record evaluation · signal processing

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  1. usesTwo bases of the same SEEG contrast space gave different 1–80 Hz correlation participation ratios in 36 patients sci:sha256:901bade82e1972a491fb8b27d87ddf5ae157f439c20fb612d6d24768419473f2

    This study used all 73 numeric input files from this covariance publication. It also used its selected public metadata, pinned EDF byte range hashes, EDF decoding code, covariance reconstruction code, and contrast-space method. The new analysis fitted pooled and path PCA and tested variance preservation in separate records.

  2. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The study used public SEEG records from OpenNeuro ds004100 version 1.1.3.

  3. doi:10.1371/journal.pcbi.1009298

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