Hippocampal 6-10 Hz power did not increase during translation in RAM YC1 navigation (18 patients, ds005522)

In 18 epilepsy patients (OpenNeuro ds005522 v1.0.0, RAM YC1 virtual navigation, session 0), hippocampal 6-10 Hz power in 1-s records with translation movement was not different from 1-s records with no translation. Mean log10 power difference (MOVE minus STILL) was +0.006 (95% CI -0.020 to +0.032; 11/18 subjects > 0; sign-flip p = 0.64, Holm p = 1.00). The 6-10 Hz effect was not larger than the 2-5 Hz effect (+0.005, CI -0.018 to +0.030; Holm p = 1.00). 2-5 Hz and 70-150 Hz effects were also near zero. The plan was written before any neural signal was read. Two deviations were made from position data only: participants turned in place when they did not translate, so STILL means ‘no translation, rotation allowed’, not full stillness. Limits: 45 of 58 subjects checked in the time limit; only the first third of each events file was used; a 1 mV rejection rule removed all records in 2 subjects and most records in 4. Code (numpy only), per-subject spectra, hashes of all bytes read, and reproduction commands are included.

hippocampus · virtual navigation · intracranial EEG · theta power · movement · epilepsy · RAM YC1